Cape Girardeau Regional Airport (CGI)

Welcome to Our Cape Girardeau Hotel. Just off I- 55 at exit 96, the Holiday Inn Express Hotel & Suites Cape Girardeau I-55 offers hotel guests 102 spacious, contemporary suites. Vacation and business guests alike choose these accommodations for a comfortable and convenient stay.

Cape Girardeau is one of those rare U.S. treasures that combine the spoils of a big city with the relaxing sensibility of small-town America. While such a description might sound confusing, consider this: Cape Girardeau has a Starbucks and a thriving town square. It has several corporate headquarters, but also a preserved historic district. In a town as wonderfully diverse as Cape Girardeau, it is fitting that Drury would set up multiple locations within.

The hotel's location is just off I-55 in southeastern Missouri, convenient to the West Park business district, as well as St. Francis Hospital and Landmark Hospital. Business travelers appreciate such amenities as free high-speed, wireless Internet access and a 24-hour Business Center with printing capabilities.

Welcome to the Victorian Inn and Suites! Located in the convenience of Cape Girardeau, the hotel provides easy access for many area attractions and items of interest in Cape. We are located just off Interstate 55 and one mile from Highway 74 that crosses the Mississippi River to Illinois.

We invite you to escape the worries of everyday life and get lost in the luxuries of our beautiful 1908 Victorian Styled home, the Rose Bed Inn. Here you will awake to the freshly brewed aroma of our House Blend coffee, ground in-house daily.

Enjoy a visit to Cape Girardeau! Located in an easily accessible area at a major I-55 exit and within blocks of shopping, health care facilities and Southwest Missouri State University. This hotel has 78 spacious guestrooms that appeal to families and is equipped for business travelers with flexible workspace. Enjoy free Continental breakfast daily and a rate that will fit your travel budget.

The Comfort Suites hotel is just under six miles from Southeastern Missouri State University, home of the Redhawks. This Jackson, MO hotel is close to a number of attractions and notable points of interest, including the Show Me Center arena, the Shawnee Park Sports Complex and the charming coastal town of Cape Girardeau.

Each of our comfortable Cape Girardeau hotel rooms includes free Wi-Fi Internet access and refrigerator. If you arrive in a truck, bus or RV, our free parking lot has plenty of space for large vehicles, and we also offer helpful amenities like guest laundry facilities. After a long stretch on the road, swim in our outdoor pool or book one of our Jacuzzi suites to unwind. Rest well overnight and help yourself to free SuperStart continental breakfast in the morning.

“Cape Girardeau is situated on a hillside, and makes a handsome appearance,” the great humorist and novelist Mark Twain said of our Missouri town. From the grand sweep of the Mississippi River to our well-preserved historic downtown, Cape Girardeau remains a handsome place to this day and attracts visitors from around the world. At the Hampton Inn hotel in Cape Girardeau, we're eager to show you around.